
What are polynucleotides?
polynucleotides are known as the future of regenerative injectables – hailed for their ability to rejuvenate and regenerate the skin, similarly to skin boosters. However, unlike skin boosters, injectable polynucleotides are renowned for their wound-healing and bio-stimulating properties. Although similar to skin boosters, polynucleotide injectables are separated and well-recognised for their complex structures and ability to rejuvenate the skin with a natural result.
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These injectables employ filtered, ultra-purified, and sterilised DNA fractions with the aim of rejuvenating the skin. Predominantly derived from salmon DNA, polynucleotides are designed to stimulate fibroblasts, promoting tissue repair, enhancing cell turnover, increasing elasticity, and stimulating collagen production. Additionally, they possess the ability to soothe inflammation and restore the balance of melanocyte activity (skin pigmentation), resulting in a more even and refreshed skin tone without adding volume like traditional dermal fillers.
What are the benefits of polynucleotides?
Unlike some injectables, polynucleotides are an exceptionally versatile and all-around treatment. With polynucleotide products developed with a host of concerns in mind, these restorative injectables can be used to treat perceived flaws across the body and face, including the eye area and stretch marks.
Excellent at boosting fibroblast production and inducing deep tissue repair processes, polynucleotides enhance the skin’s quality whilst also aiding with other concerns. Some other key usages of polynucleotides include:
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Acne scarring
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Skin conditions such as rosacea, melasma and hyperpigmentation
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Atrophic scarring
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Alopecia and androgenic hair loss
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Deep lines and sunken wrinkles
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Skin rehydration and rejuvenation
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Elastosis
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Facial ageing such as sagging and the formation of fine lines
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Lumpy scars
What polynucleotides do we offer at Cricklade Aesthetics Clinic?
- Vitaran I (under eyes only)
- Vitaran II
- Plenhyage XL Medium
- Plenhyage XL Strong
- Nucleofill Soft (under eyes)
- Nucleofill Medium
- Nucleofill Strong


Frequently Asked Questions
How many sessions will I need to notice a difference?
You can notice a small difference after 1-2 weeks but the main results will be noticeable from a few weeks after the last session.
Who should not get Polynucleotides?
If you are pregnant or breast feeding, if you're under 18 or allegeric to fish.
How often do I need to come back?
For the majority of polynucleotides 3-4 sessions are required with 2-4 weeks inbetween.